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We also demonstrated that high doses of Cetrorelix inhibited growth of androgen-independent human DU-145 and PC-3 prostate cancers transplanted into nude mice, decreased the levels and mRNA expression of EGF receptors and of IGF-II in PC-3 and DU- 145 prostate cancers 29

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Serum B12 alone can be ambiguous in the borderline range, so prescribers frequently add methylmalonic acid (MMA) and homocysteine , which both rise in true B12 deficiency